Wet granulation production process using high-speed rotary wet granulation and fluidized bed drying machine equipment combined into granulation production line, present in many domestic pharmaceutical companies have been widely used. Domestic equipment selection based on the principles of: energy saving and environmental protection. We have proposed a series of equipment requirements, including with suppliers to explore the technical feasibility in equipment selection. Here, the water powder pellet dryers recommendation, we fluidized bed URS provisions of the US FDA required standards as a reference to discuss several topics. Changzhou Heng Cheng Fusite Drying Equipment Co., Ltd. mainly produces: drying, granulation, mixing, grinding, dust, and other products, water powder pellet dryers, advantages: flash dryer, a vacuum dryer, water powder granules are dried Detailed machine, spray dryer, vibration fluidized bed dryer, air dryer, belt dryer, paddle dryer, tray dryer and the like. The main reason fluidized bed dryer to produce channeling in use in the following points: 1, the material layer particle fluidized bed drying equipment uneven distribution, excessive fine particles, drying medium and low flow rates. 2, the material is cured wet lumping uneven thickness of the material layer in the bed. Easy in bed thin, less agglomeration channeling local produce. 3, the gas distribution plate poorly designed, relatively few openings in the orifice plate, gas distribution is uneven. In the fluidized bed drying equipment, if produced in channeling will make the drying medium and the material to be dried is bad, the drying efficiency is reduced. Eliminate the phenomenon of channeling, water powder pellet dryers practical, are generally required to use a larger flow rates, reasonable distribution plate design, material not too wet, it can add a stirring device located within the bed if necessary. In the process operation, coupled with the material may be aspirated after.